Peer Reviewed Publications

Prusa, J., Zhu, D.X., and Stallings, C.L.. 2018. The stringent response and Mycobacterium tuberculosis pathogenesis. Pathogens and Disease. 76(5):fty054. PMID: 29947752.

Huynh, J.P., Lin, C., Kimmey, J.M., Jarjour, N.N., Schwarzkopf, E.A., Bradstreet, T.R., Shchukina, I., Shpynov, O., Weaver, C.T., Taneja, R., Artyomov, M.N., Edelson, B.T.*, and Stallings, C.L.*. 2018. Bhlhe40 is an essential repressor of IL-10 during Mycobacterium tuberculosis infection. The Journal of Experimental Medicine. 215(7):1823-1838. PMCID: PMC6028511. (*Co-corresponding authors) Highlighted in a JEM Insight article

Prusa, J., Jensen, D., Santiago-Collazo, G., Pope, S.S., Garner, A.L., Miller, J.J., Ruiz Manzano, A., Galburt, E.A., and Stallings, C.L.. 2018. Domains within RbpA serve specific functional roles that regulate distinct mycobacterial gene subsets. Journal of Bacteriology. 200(13):e00690-17. PMCID: PMC5996690.

Yokoyama, C., Baldridge, M., Leung, D., Zhao, G., Desai, C., Liu, T., Diaz-Ochoa, V., Huynh, J., Kimmey, J., Sennott, E., Hole, C., Idol, R., Park, S., Storek, K., Wang, C., Hwang, S., Milam, A., Chen, E., Kerrinnes, T., Starnbach, M., Handley, S., Mysorekar, I., Allen, P., Monack, D., Dinauer, M., Doering, T., Tsolis, R., Dworkin, J., Stallings, C.L., Amarasinghe, G., Micchelli, C., and Virgin, H.. 2018. LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens. Journal of Biological Chemistry. 293(16):6022-6038. PMCID: PMC5912457.

Nair, S., Huynh, J.P., Lampropoulou, V., Loginicheva, E., Esaulova, E., Gounder, A.P., Boon, A.C.M., Schwarzkopf, E.A., Bradstreet, T.R,. Edelson, B.T., Artyomov, M.N., Stallings, C.L.*, and Diamond, M.S.*. 2018. Irg1 expression in myeloid cells prevents immunopathology during Mycobacterium tuberculosis infection. The Journal of Experimental Medicine. 215(4):1035-1045. PMCID: PMC5881474. (*Co-corresponding authors)

Potter, R., Wallace, M., McMullen, A., Prusa, J., Stallings, C.L., Burnham, C., Dantas, G.. 2018. blaIMP-27 on transferable plasmids in Proteus mirabilis and Providencia rettgeri. Clinical Microbiology and Infection. In Press. PMID: 29496594.

Kinsella, R.L., Nehls, E.M., and Stallings, C.L.. 2018. Roles for autophagy proteins in immunity and host defense. Veterinary Pathology, 55(3):366-373. PMID: 29433400.

Mann, K.M., Huang, D.L., Hooppaw A.J., Logsdon, M.M., Richardson, K., Lee, H.J., Kimmey, J.M., Aldridge, B.B., and Stallings, C.L.. 2017. Rv0004 is a new essential member of the mycobacterial DNA replication machinery. PLOS Genetics. 13(11):e1007115. PMID: 29176877.

C.L. Stallings. 2017. Host response: Inflammation promotes TB growth. Nature Microbiology. 27(2):17102.PMID: 28653684.

Syal, K., Flentie, K., Bhardwaj, N., Maiti, K., Jayaraman, N., Stallings, C.L., and Chatterji, D.. 2017. Synthetic (p)ppGpp analogue: Potential inhibitor of stringent response in mycobacteria. Journal of Antimicrobial Agents and Chemotherapy. In Press. PMID: 28396544.

Kimmey, J.M., Campbell, J.A., Weiss, L.A., Monte, K.J., Lenschow, D.J., and Stallings, C.L.. 2017. The impact of ISGylation during Mycobacterium tuberculosis infection in mice. Microbes and Infection. 19(4-5):249-258. PMCID: PMC5403610.
      Selected as a highlighted open access article.

Garner, A.L., Rammohan, J., Huynh, J.P., Onder, L.M., Chen, J., Bae, B., Jensen, D., Weiss,L.A., Ruiz Manzano, A., Darst, S.A., Campbell, E.A., Nickels, B.E., Galburt, E.A., and Stallings, C.L.. 2017. Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence. JBac. 199(4). pii: e00698-16. PMCID: PMC5287406.
      Selected as for a Journal of Bacteriology Spotlight, a distinction given to the best articles in each issue.

Kimmey, J.M. and Stallings, C.L.. 2016. Bacterial pathogens versus autophagy: Implications for therapeutic intervention. Trends in Molecular Medicine. 22(12):1160-1076. PMID: 27866924.

Mann, K.M., Pride, A., Flentie, K., Kimmey, J.M., Weiss, L.A., Stallings, C.L.. 2016. Analysis of the contribution of MTP and the predicted Flp pilus genes to Mycobacterium tuberculosis pathogenesis. Microbiology. 162(10):1784-1796. PMID: 27586540.

Rammohan, J., Ruiz-Manzano, A., Prusa, J., Garner, A.L., Stallings, C.L., and Galburt, E.A.. 2016. Cooperative stabilization of Mycobacterium tuberculosis rrnAP3 promoter open complexes by RbpA and CarD. Nucleic Acids Res. 44(15):7304-13. PMCID: PMC5009747.

Flentie, K., Garner, A.G., and Stallings, C.L.. 2016. The Mycobacterium tuberculosis transcription machinery: ready to respond to host attacks. JBac.198(9):1360-73. PMCID: PMC4836228.

Kimmey, J.M., Huynh, J.P., Weiss, L.A., Park, S., Kambal, A., Debnath, J., Virgin, H.W., and Stallings, C.L.. 2015. Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection. Nature. 528(7583):565-9. PMID: 26649827.

Flentie, K.N., Stallings, C.L., Turk, J., Minnaard, A.J., Hsu, F.F.. 2016. Characterization of phthiocerol and phthiodiolone dimycocerosate esters of M. tuberculosis by multiple-stage linear ion-trap MS. J Lipid Res. 57(1):142-55. PMID: 26574042.

Watson, R.O., Bell, S.L., MacDuff, D.A., Kimmey, J.M., Diner, E.J., Olivas, J., Vance, R.E., Stallings, C.L., Virgin, H.W., and Cox, J.S.. 2015. cGAS detects Mycobacterium tuberculosis DNA to activate both type I interferon and autophagy. Cell Host & Microbe. 17(6):811-9. PMCID: PMC4466081.

Rammohan, J., Ruiz-Manzano, A., Garner, A.L., Stallings, C.L., and Galburt, E.A.. 2015. CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism. Nucleic Acids Res. In Press. PMID: 25697505.
     Selected as a Breakthrough Article, a designation given to the best papers published in Nucleic Acids Research each year

MacDuff, D.A., Reese, T.A., Kimmey, J.M., Weiss, L.A., Song, C., Zhang, X., Kambal, A., Duan, E., Carrero, J.A., Boisson, B., Laplantine, E., Israel, A., Picard, C., Colonna, M., Edelson, B.T., Sibley, L.D., Stallings, C.L., Casanova, J.L., Iwai, K., and Virgin, H.W.. 2015. Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection. Elife. In Press. PMCID: PMC4298697.

Imlay, L.S., Armstrong, C.M., Masters, M.C., Lic, T., Price, K.E., Edwards, R.L., Mann, K.M., Li, L.X., Stallings, C.L., Berry, N.G., O’Neill, P.M., and Odom, A.R.. 2015. Plasmodium IspD (2-C-methyl-D-erythritol 4-phosphate cytidyltransferase), an essential and druggable antimalarial target. ACS Infectious Diseases. In Press.

Robert Landick, Azra Krek, Michael S. Glickman, Nicholas D. Socci, and Christina L. Stallings. 2014. Genome-Wide Mapping of the Distribution of CarD, RNAP σA, and RNAP β on the Mycobacterium smegmatis Chromosome using Chromatin Immunoprecipitation Sequencing. Genomics Data. 2:110-113. PMCID: PMC4115788

Ashley L. Garner, Leslie A. Weiss, Ana Ruiz Manzano, Eric A. Galburt, and Christina L. Stallings. 2014. CarD integrates three functional modules to promote efficient transcription, antibiotic tolerance, and pathogenesis in mycobacteria. Molecular Microbiology. 93(4):682-97. PMCID: PMC4127138

Radha Gopal, Leticia Monin, Samantha Slight, Uzodinma Uche, Emmeline Blanchard, Beth A. Fallert Junecko, Christina L. Stallings, Todd A. Reinhart, Jay Kolls, Uma Nagarajan, Javier Rangel-Moreno and Shabaana A. Khader. 2014. IL-17 is required for protection against Mycobacterium tuberculosis “hypervirulent” HN878 infection. PLOS Pathogens.10(5):e1004099. PMCID: PMC4022785

Leslie A. Weiss and Christina L. Stallings. 2013. Essential Roles for Mycobacterium tuberculosis RelMtb beyond the production of (p)ppGpp. JBac. 195(24):5629-5638. PMCID: PMC3889611.

Srivastava, D. B., Leon, K, Osmundson, J, Garner, A., Weiss, L. A., Westblade, L., Glickman, M. S., Landick, R., Darst, S. A., and *Stallings, C. L., and *Campbell, E.A.. 2013. Structure and function of CarD, an essential Mycobacterial transcription factor. PNAS. 110(31):12619-24. PMCID: PMC3732983. (*Co-corresponding authors).

Roxane Tussiwand, Wan-Ling Lee, Theresa L. Murphy, Mona Mashayekhi, Jörn C. Albring, Ansuman T. Satpathy, Wumesh KC, Jeffrey A. Rotondo, Brian T. Edelson, Nicole M. Kretzer, Xiaodi Wu, Michael Behnke, Leslie A. Weiss, Samuel S.K. Lam, Cora T. Aurthur, Christina L. Stallings, L. David Sibley, Robert D. Schreiber, and Kenneth M. Murphy. 2012. BATF leucine zipper-dependent interactions with IRF factors mediate class switch recombination, TH17 development and a novel Batf3-independent pathway of CD8a+ cDC development. Nature. 490(7421):502-7.

Weiss, L. A., Harrison, P. G., Nickels, B. E., Glickman, M. S., Campbell, E. A., Darst, S. A., and Stallings, C. L. 2012. The interaction of CarD with RNAP mediates Mycobacterium tuberculosis viability, rifampicin resistance, and persistence. JBac. 194(20):5621-31.

Selected for the Journal Highlights Section of Microbe

Stallings, C. L., L. Chu, L. X. Li, and M. S. Glickman. 2011. Catalytic and non-catalytic roles for the mono-ADP-ribosyltransferase Arr in the mycobacterial DNA damage response. PLoS One. 6(7):e21807.

Barkan, D., Stallings, C. L., and Glickman, M. S. 2011. An improved counterselectable marker system for mycobacterial recombination using galK and 2-Deoxy-Galactose. Gene. 470(1-2):31-6.

Stallings, C. L., N. C. Stephanou, L. Chu, A. Hochschild, B. E. Nickels, and M. S. Glickman. 2009. CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistence. Cell. 138(1):146-59.

Comments in:
L.E. Connolly and J.S. Cox. 2009. Cell Host Microbe. 6(1):1-2.
S. Molloy. 2009. Nature Reviews Microbiology. 7:618.

Stallings, C. L. and Silverstein, S. J. 2006. Posttranslational modification and cell-type specific degradation of varicella-zoster virus ORF29p. J Virol. 80:10836-46.

Stallings, C. L., G. J. Duigou, A. A. Gershon, M. D. Gershon, and S. J. Silverstein. 2006. The cellular localization pattern of varicella-zoster virus ORF29p is influenced by proteasome- mediated degradation. J Virol. 80:1497-1512.

Stallings, C. L. and Silverstein, S. J. 2005. Dissection of a novel nuclear localization signal in open reading frame 29 of varicella-zoster virus. J Virol. 79:13070-81.

*Stallings, C. L. and Glickman, M. S. 2011. CarD: A new RNA polymerase modulator in mycobacteria. Transcription. 2(1):15-18. (*Corresponding Author)

Stallings, C. L. and M. S. Glickman. 2010. Is Mycobacterium tuberculosis stressed out? A critical assessment of the genetic evidence. Microbes and Infection. 12(14-15):1091-101.

Book Chapters

Walters, M.S., Kyratsous, C.A., Stallings, C.L, Lungu, O. and Silverstein, S.J. "What Doesn't Belong and Why; a Saga of Latency Associated Proteins Elaborated by Varicella Zoster Virus". In: From the Hallowed Halls of Herpesvirology: A Review Series Commemorating the 80th Birthday of Bernard Roizman, Sc.D., J.A. Blaho and J.D. Baines editors, World Scientific Publishing/ Imperial College Press, City, In press.